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Invasive basal cell carcinoma

Introduction: Basal cell carcinoma (BCC) is the most common skin cancer. It is primarily a local disease, and it very rarely causes metastatic disease. Chemotherapeutic agents had limited success in management of metastatic disease until the introduction of vismodegib Basal cell carcinoma Basal cell carcinoma is a type of skin cancer. Basal cell carcinoma begins in the basal cells — a type of cell within the skin that produces new skin cells as old ones die off. Basal cell carcinoma often appears as a slightly transparent bump on the skin, though it can take other forms Infiltrating Basal Cell Carcinoma of Skin occurs as an irregular plaque and has the tendency to infiltrate deep into the body tissue, making them difficult to treat. It is an uncommon subtype of BCC of Skin Some lesions may grow to large sizes and ulcerate. They can also infiltrate into the adjoining soft tissues and nerves Basal cell carcinoma is most often treated with surgery to remove all of the cancer and some of the healthy tissue around it

Invasive Basal Cell Carcinoma of the Skin Treated

  1. Basal cell carcinoma (BCC) is the most common skin cancer though usually not a lethal or metastatic disease. BCC can be associated with significant morbidity secondary to local invasion and destruction. 1 Incidence of BCC is 226 per 100,000, and age-adjusted prevalence is up to 343 per 100,000 people. 2 Ultraviolet light exposure is the main.
  2. Basal cell carcinoma: This is the most common skin cancer and tends to occur in sun exposed areas of the body. If left untreated it tends to grow and invade neighboring str..
  3. Cryotherapy (cryosurgery) can be used for some small basal cell carcinomas, but it's not usually recommended for larger tumors or those on certain parts of the nose, ears, eyelids, scalp, or legs. Cryotherapy can also be used to treat large tumors in one treatment session to relieve symptoms from the cancer
  4. Basal cell carcinoma (also called basal cell skin cancer) is most common type of skin cancer. About 8 out of 10 skin cancers are basal cell carcinomas (also called basal cell cancers). These cancers start in the basal cell layer, which is the lower part of the epidermis
  5. Basal cell carcinoma (BCC) is the most common form of skin cancer. In general, these tumors are locally destructive, invading and destroying surrounding healthy skin and tissues, but rarely metastasizing and spreading into the body
  6. Infiltrative basal cell carcinoma is an aggressive type of skin cancer that requires surgical treatment. Subtypes of infiltrative basal cell lesions include micronodular carcinoma and morpheaform carcinoma

Basal cell carcinoma (BCC) is the most common paraneoplastic disease among human neoplasms. The tumor affects mainly photoexposed areas, most often in the head and seldom appears on genitalia and perigenital region Stockfleth E, Ulrich C, Hauschild A, Lischner S, Meyer T, Christophers E. Successful treatment of basal cell carcinomas in a nevoid basal cell carcinoma syndrome with topical 5% imiquimod. Eur J. Basal Cell Carcinoma Staging. Staging is the process of determining whether cancer has spread and, if so, how far. The stage of the disease may affect the treatment plan. The stage is based on the size of the tumor, how deeply into the skin it has grown, and whether cancer has spread beyond the tumor to the lymph nodes Basal Cell Carcinoma (BCC) of Skin is a malignant cancer affecting the skin. It is a slow-growing tumor generally observed in older individuals, in both men and women This malignant carcinoma, which may be present as a lesion on the sun-exposed areas of the body, has the potential to metastasize (spread) to the lymph node Basal cell carcinoma (BCC) is a common, locally invasive, keratinocyte cancer (also known as nonmelanoma cancer). It is the most common form of skin cancer. BCC is also known as rodent ulcer and basalioma. Patients with BCC often develop multiple primary tumours over time

Basal cell carcinoma (BCC) is the most common skin cancer. Eight out of 10 skin cancers are basal cell carcinomas. It grows very slowly and is very treatable. 7 Can BCC be cured Basal cell carcinoma. This is the most common form of all cancers. It occurs in cells lining the deepest part of the skin's outer layer. You should get quick treatment for basal cell carcinoma to.. Of the nonmelanomas, basal cell carcinoma (BCC) constitutes about 80% of the cancers diagnosed every year. BCC usually occurs in sun-exposed areas such as the face and extremities. Occurrence in the nipple areolar complex is very rare

Basal cell carcinoma (BCC) is the most common form of skin cancer. It originates in basal cells, which are located in the epidermis, which is the outermost layer of the skin, that are responsible for producing new skin cells and pushing them to the surface Basal cell carcinoma (BCC) - The most common form of skin cancer, these tumors develop in the skin's basal cells, which line the deepest layer of the epidermis - the outermost layer of your skin Basal cell carcinoma can look different. You may notice a skin growth in a dome shape that has blood vessels in it. It can be pink, brown, or black. At first, a basal cell carcinoma comes up like a small pearly bump that looks like a flesh-colored mole or a pimple that doesn't go away

Basal cell carcinoma - Symptoms and causes - Mayo Clini

Basal-cell carcinoma (BCC), also known as basal-cell cancer, is the most common type of skin cancer. It often appears as a painless raised area of skin, which may be shiny with small blood vessels running over it. It may also present as a raised area with ulceration Basal Cell Carcinoma Lifetime ambient ultraviolet radiation exposure and risk of basal cell carcinoma by anatomic site in a nationwide US cohort, 1983-2005 Cancer Epidemiology, Biomarkers & Prevention | Jul 2 This technique is used less commonly for invasive BCC because it may miss deeper portions of the tumor, and because scar tissue at the site can make a recurrence harder to detect. Cemiplimab is used to treat patients with advanced basal cell carcinoma (BCC) previously treated with a hedgehog pathway inhibitor (HHI) or for whom an HHI is not. Treatment for invasive squamous cell carcinoma includes surgery. Squamous cell carcinoma is the second most common type of skin cancer after basal cell carcinoma. Most often it is caused by exposure to UV rays, either through natural sunlight or by indoor tanning. People with fair skin are particularly susceptible

Infiltrating Basal Cell Carcinoma of Skin - DoveMe

For basal cell carcinoma staging, the factors are grouped and labeled 0 to 4. The characteristics and stages of basal cell carcinoma are: Stage 0: Also called carcinoma in situ, cancer discovered in this stage is only present in the epidermis (upper layer of the skin) and has not spread deeper to the dermis A new tool to inform intra-operative decision making in skin cancer treatment: the non-invasive assessment of basal cell carcinoma of the skin using elastic scattering spectroscopy T Upile 1,2 , W Jerjes 3 , O Johal 2 , S Lew-Gor 2 , J Mahil 1 , H Sudhoff

Recurrent Extensive Basal Cell Carcinoma of Forehead

Basal cell carcinoma - Diagnosis and treatment - Mayo Clini

Definition / general. Basal cell carcinoma (BCC) arises from the interfollicular or follicular epithelium. Most common malignant tumor type in humans. Local aggressive course. Low disease associated death rate; metastases to lung and bone exceptionally rare Basal Cell Carcinoma (BCC) affects over 2 million individual new cases diagnosed in the U.S. each year, making it one of the most common forms of non-melanoma related skin cancer. Although surgery is considered one of the most common treatments for BCC, non-surgical treatments are available and can be a reliable therapeutic option

Invasive ductal carcinoma (IDC), also known as infiltrating ductal carcinoma, is cancer that began growing in a milk duct and has invaded the fibrous or fatty tissue of the breast outside of the duct. IDC is the most common form of breast cancer, representing 80 percent of all breast cancer diagnoses The longer basal cell carcinoma goes untreated, the procedures necessary to remove it become more advanced, invasive, and costly. To receive treatment in the earliest stages, patients should let their dermatologist know if they notice small bumps that have a shiny or pearly appearance Basal cell carcinoma (BCC) is the most common form of skin cancer, with an estimated 4.3 million cases diagnosed in the United States each year (PDQ Adult Treatment Editorial Board, 2018).Although it rarely metastasizes, BCC can cause significant local tissue destruction, resulting in disfigurement and infiltration into vital underlying structures if left untreated

The SRT-100™ treats basal cell carcinoma, and patients have no downtime or lifestyle restrictions following treatment. The U.S. Food and Drug Administration has approved the SRT-100™ as a safe and effective treatment for basal cell skin cancer. The procedure takes just minutes in a physician's office and offers the same cure rates as. The medical term for this is advanced basal cell carcinoma. It's also possible for BCC to spread to other parts of your body, but this is rare. When the cancer spreads, it typically travels first to the lymph nodes closest to the tumor. From there, it tends to spread through the blood to bones, the lungs, and other parts of the skin Basal Cell Carcinoma. Basal cell carcinoma (BCC) is the most common type of skin cancer and the least dangerous. It is locally invasive, slowly eating away at the surrounding tissue, and may eventually become an ulcerated, bleeding sore. The predominant factor causing BCC is UV radiation from the sun

What does invasive basal cell carcinoma mean Answers

Learning objectives. Describe clinical features and management of basal cell carcinoma.; Introduction. Basal cell carcinoma (BCC) is by far the most common cancer in humans. It may arise in habitually sun-exposed skin, especially on the face, or on areas that have been previously sunburned such as the back.Although most common in middle-aged and elderly, in New Zealand young adults also. A basal cell carcinoma (BCC) is a type of skin cancer. There are two main types of skin cancer: melanoma and non-melanoma skin cancer. BCC is a non-melanoma skin cancer, and is the most common type (greater than 80%) of all skin cancer in the UK. BCCs are sometimes referred to as 'rodent ulcers' Basal-cell carcinoma (BCC) is a slow-growing, locally invasive malignant epidermal skin tumour. The lesion infiltrates tissues in a three-dimensional fashion [ 1 ] through the irregular growth of subclinical finger-like outgrowths which remain contiguous with the main tumour mass [ 2 , 3 ] Radiation therapy is a treatment option for basal cell carcinoma that involves using high-energy rays to destroy cancerous cells. While surgery is most commonly the primary treatment used for this type of cancer, there are circumstances when radiation therapy may be used as the first treatment Thank you for your question. Mohs surgery is typically reserved for squamous cell cancers and basal cell cancers (and some other more rare types of cancers as well) on the face in areas where preserving normal and unaffected tissue. I hope this helps

Possible Basal Cell Carcinoma, From Janet in Australia (Capital Territory) I first started searching the internet for the definition of BCC when I returned home one day from my general practitioner (GP) and she questioned as to whether the fleshy coloured growth that had appeared quite rapidly under my right eye was indeed BCC Basal cell carcinoma (BCC), also known as basal cell epithelioma, is the most common form of skin cancer. Basal cell carcinoma usually occurs on sun-damaged skin, especially in light-skinned individuals with a long history of chronic sun exposure. Although it requires treatment to prevent it from becoming too invasive, basal cell carcinoma does. Browse 1,074 basal cell carcinoma stock photos and images available, or search for skin cancer or squamous cell carcinoma to find more great stock photos and pictures. Nodular basal cell carcinoma on the shoulder. Basal cell carcinoma, nodular in the nasal groove. Basal Cell Carcinoma Basal cell carcinoma is the most common skin cancer. There are millions of these every year in this country alone, much less worldwide. They are usually not very dangerous although they can be quite invasive, destructive and disfiguring. Most of these occur on the face but they can occur anywhere, even in areas where the sun does not shine.. Basal Cell Carcinoma also referred to as BCC, is the most common cancer in Australia. They account for around 80% of all non-melanoma skin cancers. In 2016 it is estimated that there were 600,000 Basal Cell Carcinomas. When treated early the vast majority of Basal Cell Carcinomas are not life-threatening

Treating Basal Cell Carcinoma Basal Cell Skin Cancer

Basal cell carcinomas and squamous cell carcinomas are forms of skin cancer that are less invasive and less likely to spread than melanomas, but they still need to be diagnosed, treated, and prevented.. Basal cell carcinoma (BCC) is the most common form of skin cancer.It is classified as a non-melanoma form of the condition, and accounts for about 75 percent of all skin cancer cases D. Tall cell carcinoma with reversed polarity and Mucinous cystadenocarcinoma NOS are two new entities Tall cell carcinoma with reversed polarity is a rare subtype of invasive breast carcinoma characterized by tall columnar cells with reversed nuclear polarity, arranged in solid and solid papillary patterns, and most commonly associated with IDH2p.Arg172 hotspot mutations The introduction of global gene expression analysis in breast cancer research has focused attention onto a repeatedly described subgroup of invasive breast cancer, the basal-like carcinomas. This subgroup is characterised by the expression of high-molecular weight cytokeratins 5, 14 and 17; using immunohistochemical diagnosis, it represents approximately 7-20% of invasive breast cancers Basal cell carcinoma is the most common type of cancer, with incidence estimates ranging from 124 to 849 per 100,000 persons per year, depending on geographic location. 2 The age-adjusted. Medical studies indicate that for treatment of 104 skin cancers (75 basal cell carcinomas and 29 squamous cell carcinomas), this treatment method had a success rate of 96 percent for the five-year cure rate. Chemotherapy Creams. Some chemotherapy creams may be applied directly on the skin for basal cell carcinomas and actinic keratosis skin cancer

What Are Basal and Squamous Cell Skin Cancers? Types of

Basal cell carcinoma or basal cell skin cancer is the most common form of skin cancer. It develops directly from the basal cells found in the bottom layer of the epidermis and around the hair follicles. A common risk factor for this type of cancer is sunlight damage to the skin; therefore, basal cell carcinoma most commonly develops on the face. Chemotherapy may be used to treat basaloid squamous cell carcinoma. When examined under a microscope, tissue samples exhibit both basal and squamous cells. Both cell types must be present for a definitive diagnosis. The basal cells appear as oval, polyhedral, or round shapes in rosette, ribbon, or rod formations When compared to IG-SRT, Squamous cell carcinoma surgery and Basal cell cancer Mohs surgery is more invasive in several ways. Surgery requires cutting that will likely leave a scar, and the patient will need to be on antibiotics following the procedure

The incidence of basal cell and squamous cell carcinomas, which also are called nonmelanoma skin cancer, has been increasing steadily over the past 30 years.1, 2 The reasons for this increase. NOTE: There are different treatments for Basal Cell Carcinoma (BCC) based on the stage of the skin cancer. Some treatments include Curettage and Electrodesiccation, Excision, Mohs Surgery, or Radiation. The first two procedures are not as invasive as Mohs Surgery and can be done in office An updated review of management of nevoid basal cell carcinoma syndrome (NBCCS) is presented. An ideal treatment of NBCCS does not exist, and surgical intervention has been the most commonly used treatment, as it provides excellent cure rates Basal cell carcinoma is the most common type of skin cancer afflicting close to a million patients a year. The head and neck region is a particularly common location for diagnosis of basal cell carcinoma. Within this region, the nose is one of the more frequently afflicted locations Dr. Brian Lawenda answered. 24 years experience Radiation Oncology. A common skin cancer: Basal cell carcinoma is the most common skin cancer type. It is frequently slow growing. They rarely metastasize. Typically, they occur in areas of th Read More. 2 doctors agree. 0

Invasive squamous cell carcinoma skin cancer - Skin injuries keratosis actinic and melanoma. Acinetus keratosis and basal-cellular carcinoma are easily cut and have a very good prediction, while CSCC has a bad prediction, especially when the lymph nodes and adjoining vital structures are invaded squamous cell carcinoma (SCC) starts in the cells lining the top of the epidermis and accounts for about 20 in every 100 skin cancers; Basal cell carcinoma. Basal cell carcinoma (BCC) usually appears as a small, shiny pink or pearly-white lump with a translucent or waxy appearance. It can also look like a red, scaly patch ↑ 2.0 2.1 2.2 Squamous-cell carcinoma in situ is essentially equivalent to and used interchangeably with the term Bowen's disease.(Yanofsky, 2011) ↑ The excision example shows a superficial basal cell carcinoma. ↑ - Buschke-Löwenstein tumor is an alternative name for verrucous squamous cell carcinoma in the ano-genital region

The 5-year disease-free survival rate was 45.5% in metaplastic breast carcinoma versus 71.2% in invasive ductal carcinoma, and 60.3% in triple-negative invasive ductal carcinomas (P <0.001) We used tumor-like EGF and stiffness conditions to interlink CP regulation with invasive cell transition. In non-invasive acini, actin CPs originated from the cortical actin network in the lateral basal cell layer and interacted with the BM. In invasion-triggered acini, two cell populations were discovered at the BM-ECM interface

The clinical picture, treatment and course of invasive, aggressive basal cell terebrans carcinoma of the face, scalp and neck in eight patients is presented in detail. Based on the analysis of these patients, as well as our experience of a total of 93 patients with aggressive, invasive basal cell carcinoma, treated so far, the conclusion is reached that basal cell terebrans carcinoma develops. A, Computed tomographic orbits demonstrated a 2.4 × 3.3-cm left orbital mass enveloping the optic nerve and eroding the orbital roof. B, A light micrograph (hematoxylin-eosin, original magnification ×100) shows peripheral palisading within and artifactitious separation from frontal bone marrow, consistent with invasion by basal cell carcinoma Basal Cell Carcinoma Diagnosis. An infiltrative basal cell carcinoma under the microscope. This type of basal cell often occurs on the face. MSK's Mohs surgeons are experts in treatment option for facial skin cancers. You know your skin best, so it makes sense that you would notice any changes before anyone else Basal cell carcinoma (BCC) is the most common cancer in humans and the most common cancer of the skin. Two million Americans are diagnosed with BCC every year. It is a neoplasm of basal keratinocytes that is found more frequently in men than women. Rates of BCC have been increasing over the last several decades, particularly in young women Basal cell carcinoma (BCC) is the most common form of skin cancer. It is a malignant epidermal tumour which is slow-growing, locally invasive, and mainly affects white people. Though it is malignant, metastasis is extremely rare. However it is locally invasive and destructive hence also referred to as rodent ulcer

What are the Subtypes of Basal Cell Carcinom

For the first time, researchers have identified epidermal stem cells as the cell of origin of basal cell carcinoma (BCC) in a mouse model, and mapped the cellular dynamics that lead to tumor. A patient in his sixties noticed a small bump along the left tip of his nose. When he saw his primary care physician he was referred to a dermatologist. A shave biopsy of the lesion was performed and found to be positive for basal cell carcinoma, the most common form of skin cancer Basal cell carcinoma and squamous cell carcinoma are the two most common types of skin cancers. According to the American Cancer Society, over 5 million cases of basal cell and squamous cell cancers are diagnosed every year.Though, basal cell carcinoma occurs more often, taking credit for about 80% of these cases Basal Cell Carcinoma is the more frequent form of non-melanoma cancer of the skin. It is also the easiest to treat as well as the least probable to broaden. Even though this type of carcinoma is hardly ever fatal, it may cause harm which is extensive to tissue in the surrounding area as well as the bone if it is not eradicated

Medical studies indicate that for treatment of 104 skin cancers (75 basal cell carcinomas and 29 squamous cell carcinomas), this treatment method had a success rate of 96 percent for the five-year cure rate. Chemotherapy Creams. Some chemotherapy creams may be applied directly on the skin for basal cell carcinomas and actinic keratosis skin cancer Choi et al. define three molecular subtypes of muscle-invasive bladder cancer, a disease with heterogeneous clinical outcomes and responses to conventional chemotherapy. Luminal and basal subtypes resemble the equivalent molecular subtypes of breast cancer, whereas a p53-like subtype displays chemoresistance Basal cell carcinomas may appear to heal on their own but inevitably will recur. Common symptoms of basal cell carcinoma include: Round, dome-shaped or flat scaling bumps. Pink to red, pearly or translucent. Rolled borders. Visible superficial blood vessels. A sore that oozes and bleeds

Intraductal carcinoma of the prostate - Libre Pathology

Types of Basal Cell Cancer: Nodular, Superficial, and

Basal cell carcinoma (BCC) is the most common skin cancer in humans, which typically appears over the sun-exposed skin as a slow growing, locally invasive lesion that rarely metastasizes Basal cell carcinoma (BCC) is a type of skin cancer that begins in the basal cells. Normal basal cells line the epidermis. They're the skin cells that replace old cells with new ones. Cancer of.

Clinical variants, stages, and management of basal cell

CK5/6+ / p63+ breast intraductal papillomas show less risk of subsequent invasive carcinoma (Pathol Int 2015;65:81) Diffuse positivity in DCIS defines basal-like subtype with poorer prognosis (Hum Pathol 2007;38:197) CK5/6 positivity helps define a basal-like subtype of triple negative breast carcinoma (TNBC) with poorer prognosis (Clin Cancer Res 2006;12:1533); associated with premenopausal. 1) Nodular: this is the most common subtype of basal cell cancer and usually presents as a pearly nodule with defined borders and dilated blood vessels, often with central ulceration 2) Superficial: this is the least invasive of the basal cell carcinoma subtypes. It typically presents as a slowly enlarging erythematous, scaling plaque

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Video: How is infiltrative basal cell carcinoma characterized

Basal Cell Carcinoma Stages Stanford Health Car

Basosquamous Cell Carcinoma. March 21, 2011. Metatypical basosquamous cell carcinoma is a subset of cutaneous cancers that poses an increased risk of metastases to the patient due to its aggressive behavior. The classic histology of metatypical basosquamous cell carcinoma includes features of both basal cell carcinoma and squamous cell. Squamous Cell Carcinoma FAQs. Basal Cell Carcinoma FAQs. The American Society of Mohs Surgery supports the medical community with shared knowledge among members, as well as educational courses. Learn more about these offerings at (800) 616-2767. If you are a patient looking for a Mohs surgeon in your area, visit our directory Basal Cell Carcinoma is the most common type of cancer found in the United States, affecting up to 800,000 people annually. This cancer is related, but not dependent on UV exposure and therefore, generally affects older adults with fair skin. It can appear in younger patients, as well. It usually appears as a pearly, pink, flat area or nodule.

Skin CancersPathology Outlines - Cytokeratin 5/6 and CK5» Squamous Cell Carcinoma Invasive Atlas

Nodular Basal Cell Carcinoma of Skin - DoveMe

More than 95% of these carcinomas occur in patients over 40. They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck and the remaining 15% on the trunk and extremities. Basal cell carcinoma usually grows in a slow and indolent fashion In the present study, the researchers sought to develop and assess a deep learning-based artificial intelligence model to automatically detect basal cell carcinoma (BCC) in reflectance confocal microscopy (RCM), a non-invasive diagnostic technique that can image skin lesions at the cellular level resolution, images Metformin, even in low doses, may be associated with a decreased risk for basal cell carcinoma, according to a study. Metformin is an oral medication used mostly for type 2 diabetes mellitus. Basal cell carcinoma is skin cancer. This type of cancer has shown increasing number of the people who are affected with it. People with white skin are more likely to get basal cell carcinoma. The main reason for this disease is the high UV radiation which comes from the sunlight (the highest UV radiation is [ Basal cell carcinoma (BCC) is the most common cutaneous skin malignancy. BCC generally has a clinical course characterized by slow growth, minimal soft tissue invasiveness, and a high cure rate. Occasionally, however, BCC behaves aggressively with deep invasion, recurrence, and potential regional and distant metastasis. Several factors, including tumor size, duration, histology, and perineural.

Primary Basal Cell Carcinoma of the Caruncle | Dermatology

Squamous cell carcinoma (SCC) is the second most common cutaneous malignancy after Basal Cell Carcinoma with an increasing incidence worldwide. It usually arises on sun-exposed areas of the skin, such as scalp, face, neck, forearms and dorsal hands. YouTube. Dermoscopy Level 1: Disease-based learning. 4.73K subscribers There are 5 Stages of Squamous Cell Skin Cancer Stage 0 is Carcinoma in situ. This stage is not considered invasive cancer as the abnormal cells are only in the upper layer of the skin, the epidermis. Stage 1 and 2. This stage is determined by how big the cancer is and if there is high-risk features of the tumor. Stage Basal Cell Carcinoma (BCC) is the most common type of skin cancer. Fortunately it is usually the least dangerous and almost always completely curable by treatment. BCC accounts for more than three-quarters (75%) of all skin cancers. Most basal cell carcinomas are slow-growing and almost never spread to other parts of the body There are three main types of skin cancer: Basal cell carcinoma (BCC). Squamous cell carcinoma (SCC). Melanoma. BCC and SCC are the most common forms of skin cancer and together are referred to as nonmelanoma skin cancers. This summary addresses the treatment of BCC and SCC of the skin and the related noninvasive lesion actinic keratosis The simultaneous presence of two disparate neoplasms occurring in the same specimen has been well documented, albeit uncommonly. The juxtaposition of malignant melanoma and basal cell carcinoma (BCC) has been rarely reported in case reports, with most cases describing melanoma in situ and BCC. We present two cases of invasive melanoma (Clark level IV, no microscopic satellites present.